Efficacy of antidotes (midazolam, atropine and HI-6) on nerve agent induced molecular and neuropathological changes
نویسندگان
چکیده
منابع مشابه
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15 صفحه اولThe effect of HI-6 on reversal or prevention of changes induced by paraoxon in the function of Chicken biventer cervices nerve-muscle preparation
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Paralysis of skeletal muscles, which can lead to paralysis of respiratory muscles and death, is one of the most toxic effects of organophosphates, and oximes are almost the only known antidotes that can reverse or prevent such toxic effects. In the present research work, possible reversal or preventive effect of different concentrations of the relatively new oxime (HI-6) on changes induced by p...
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Midazolam: an Improved Anticonvulsant Treatment for Nerve Agent-induced Seizures
The drug midazolam has been recommended to replace diazepam as the immediate anticonvulsant treatment for nerve agent-induced seizures. This recommendation marks the latest decision in an ongoing program to improve medical countermeasures to treat nerve agent poisoning. Extensive rodent screening studies first identified midazolam as the most promising compound to focus on for advanced testing....
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ژورنال
عنوان ژورنال: BMC Neuroscience
سال: 2014
ISSN: 1471-2202
DOI: 10.1186/1471-2202-15-47